If you ask a new .NET developer (from the Access or VB6 world) what is the best thing about .NET Windows Forms, most of your answers will be "Form Inheritance" that allows them to keep a nice consistent look for all forms. If you ask them a couple of months later, they will probably tell you the worst thing about .NET Windows Forms is "Form Inheritance". This is because they have had too many problems with the bugs in the form designer regarding this feature. Many abandon them altogether and jump on the user control band wagon. Please don't... we have a solution to this...
If you can keep the level of form inheritance to a minimum, then you may not see the problem or at least you will experience the problem less. Anyway even if you do, stop whinging and just close down Visual Studio.NET and restart. You don't change the base form that often anyway.
Well how do you keep it to a minimum? Well make the first base form without any controls, only code (to make it as flexible as possible and avoid having a multitude of base forms).
We try to keep the number of controls on inherited forms, and the levels of inheritance to a minimum, because it reduces the risk of problems with the Visual Studio Designer (you know when the controls start jumping around, or disappearing from the Designer, or properties getting reset on inherited copies or even the tab order getting corrupted). Designer errors can also occur in the task list if the InitializeComponent method fails.
Every form in your application should inherit from a base form which has code common to every form, for example:
Figure: Base Form for all SSW applications with SSW icon
a) Sorting out the StartPosition:

b) Sorting out FormBorderStyle:

We have a program called SSW CodeAuditor to check for this rule.
c) Sorting out a base data entry form:
Figure: Base data entry form with menu, toolbar and OK, Cancel & Apply buttons
Note: The data entry base form has no heading - we simply use the Title Bar.
We have a program called SSW .NET Toolkit that implements inherited forms.